小儿中毒性表皮坏死松解症15例临床分析

本文对１５例小儿中毒性表皮坏死松解症（ＴＥＮ）进行回顾性分析。男性７例,女性８例,剥脱面积占体表面各４５％￣９８％不等。１５例患者均有用药史,致敏药物以镇静抗癫痫药物为首,死亡１例,后遗症５例。归纳总结出小儿ＴＥＮ的诊断标准。关于皮腩类固醇激素在治疗ＴＥＮ中的应用,我们认为早期短期应用是必要的,主意纠正水、盐、电解质平衡的紊乱,营养的供应和皮肤粘膜的护理。

Clinical study of 15 children toxic epidermal necrolysis

A study of children toxic epidermal necrolysis(TEN)was carried out.fifteen children who are seven boys and 7 girls are report.The areas of denudation are about 45%-98%.The drug most commonly involved was sedative anticonvulsant.There was one death and five sequel patients,the mortality for TEN was 6 1%,sequel rate was 35%.From the fifteen samples,a standard was derived.In the treatment of children TEN,we think it is necessary to use corticosteroids at early stages for a short duration,supply fluid and electrolytes and nutrients and give adequate nursing care of shin and mucous menbrance.