| 阿托伐他汀对不稳定心绞痛患者血清基质金属蛋白酶-9和高敏C-反应蛋白的影响 |
| |
| 引用本文： | 杨春庆. 阿托伐他汀对不稳定心绞痛患者血清基质金属蛋白酶-9和高敏C-反应蛋白的影响[J]. 中国实用医药, 2009, 4(32): 3-4 |
| |
| 作者姓名： | 杨春庆 |
| |
| 作者单位： | 山东省泰安市红十字会中心血站,271000 |
| |
| 摘 要： | 目的了解阿托伐他汀对不稳定心绞痛患者血清基质金属蛋白酶-9（MMP-9）和高敏C-反应蛋白（hs-CRP）的疗效。方法50例确诊为不稳定心绞痛的患者给予阿托伐他汀20mg治疗，分别于治疗前、治疗4周、12周时测患者血清MMP-9和hs-CRP浓度。结果阿托伐他汀治疗4周后患者血清MMP-9和hs—CRP浓度较治疗前明显下降（P〈0．05），12周时MMP-9和hs—CRP较4周时明显下降（P〈0．05）。结论阿托伐他汀能有效降低不稳定心绞痛患者血清MMP-9和hs-CRP的浓度，而且随着治疗时间的延长，MMP-9和hs-CRP进一步降低。
|
| 关 键 词： | 阿托伐他汀 基质金属蛋白酶-9 高敏C-反应蛋白 |
Effect of Atorvastatin on MMP-9 and high-sensitivity C-reactive protein(hs-CRP)of the patients with unstable angina |
| |
| YANG Chun-qing. Effect of Atorvastatin on MMP-9 and high-sensitivity C-reactive protein(hs-CRP)of the patients with unstable angina[J]. China Practical Medical, 2009, 4(32): 3-4 |
| |
| Authors: | YANG Chun-qing |
| |
| Affiliation: | YANG Chun-qing. (Tai＇an City ,Shandong Province,Red Cross Blood Center, Tai＇an 271000,China) |
| |
| Abstract: | Objective To study the effect of Atorvastatin on MMP-9 and high-sensitivity C-reactive protein（hs-CRP）of the patients with unstable angina. Methods 50 patients with unstable angina were treated with Atorvastatin. Serum levels of MMP-9 and hs-CRP were monitored at the beginning and after 4,12 weeks of treatment. Results After 4 weeks of treatment the decrease of serum MMP-9 and hs-CRP were significantly （P 〈 0. 05 ）. At the end of 12 weeks the decrease of serum MMP-9 and hs-CRP were significantly compared with that of 4 weeks（P 〈0. 05）. Conclusion Atorvastatin treatment lowered the serum MMP-9 and hs-CRP effectively. |
| |
| Keywords: | Atorvastatin MMP-9 High-sensitivity C-reactive protein |
| 本文献已被 维普 万方数据 等数据库收录！ |
