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环孢素A联合化疗方案治疗复发、难治性白血病
引用本文:王全顺,周绮,于力,达万明,楼方定. 环孢素A联合化疗方案治疗复发、难治性白血病[J]. 白血病.淋巴瘤, 2002, 11(1): 18-20. DOI: 10.3760/cma.j.issn.1009-9921.2002.01.006
作者姓名:王全顺  周绮  于力  达万明  楼方定
作者单位:解放军总医院,北京 100853;解放军总医院,北京 100853;解放军总医院,北京 100853;解放军总医院,北京 100853;解放军总医院,北京 100853
摘    要:目的:探讨用环孢素A联合化疗方案治疗复发、难治性白血病的疗效。方法:18例急性非淋巴细胞白血病患者,采用CsA+DA方案治疗6例,CsA+MAE方案治疗12例。结果:CsA+DA组完全缓解率为33%。CsA+MAE组完全缓解率为50%。两组病例的有效率及完全缓解率经统计学分析没有显著差异,P值均大于0.5。结论:环孢素能够逆转难治性白血病的耐药性,在难治性白血病的治疗中有一定作用,但缓解后的治疗需要引起重视。

关 键 词:急性非淋巴细胞白血病  难治性  化疗  环孢素A
文章编号:1009-9921(2002)01-0018-03
修稿时间:2001-12-15

CsA Assdciated with Chemotherapy in the Treatment of Refractory Acute Leukemia
WANG Quan shun,ZHOU Qi,et al.. CsA Assdciated with Chemotherapy in the Treatment of Refractory Acute Leukemia[J]. Journal of Leukemia & Lymphoma, 2002, 11(1): 18-20. DOI: 10.3760/cma.j.issn.1009-9921.2002.01.006
Authors:WANG Quan shun  ZHOU Qi  et al.
Affiliation:WANG Quan shun,ZHOU Qi,et al.General hospital of PLA
Abstract:Objective:To study the CsA associated with chemotherapy in the treatment of refractory acute myeloblastic leukemia.Methods:18 cases of acute myeloblastic leukemia has treated in the regime of cyclosporin A(CsA) associated with chemotherapy.Results:The ratio of complete remission were separately 33 % and 50 % in the cases treated with CsA+DA and CsA+MAE.The difference between results of two treatment has no statiatic sence.Conclusion:CsA associated with chemotherapy is a effective considerable regimen in treatment of refractory acute myelogenous leukemia.
Keywords:Refractory acute myelogenous leukemia  Cycloposporin A  Chemotherapy
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