| 充血性心力衰竭患者血浆一氧化氮和肿瘤坏死因子含量变化及其意义 |
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| 引用本文： | 梁伟钧,符益冰,陈建英.充血性心力衰竭患者血浆一氧化氮和肿瘤坏死因子含量变化及其意义[J].中国综合临床,2001,17(12):907-908. |
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| 作者姓名： | 梁伟钧 符益冰 陈建英 |
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| 作者单位： | 广东医学院附属医院心内科, |
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| 摘 要： | 目的：探讨充血性心力衰竭（CHF）患者血浆一氧化氮和肿瘤坏死因子（TNF）含量变化及其意义。方法：检测68例充血性心力衰竭患者血浆一氧化氮和TNF含量，选择30例健康体检者作对照组。结果：CHF患者血浆一氧化氮和TNF水平明显高于对照组（P＜0．01），且心力衰竭程度越重，血浆一氧化氮与TNF水平越高。结论：血浆一氧化氮和TNF增高是CHF病理生理特征之一；一氧化氮与TNF增高可作为判断心功能级别的一个重要指标。
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| 关 键 词： | 充血性心力衰竭 一氧化氮 肿瘤坏死因子 |
| 文章编号： | 1008-6315(2001)12-0907-02 |
| 修稿时间： | 2001年7月11日 |
Clinical study of change s of plasma nitric oxide and tumor necrosis factor levels in patients with conge stive heart failure |
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| Liang Weijun,Fu Yibing,Chen Jianying.Clinical study of change s of plasma nitric oxide and tumor necrosis factor levels in patients with conge stive heart failure[J].Clinical Medicine of China,2001,17(12):907-908. |
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| Authors: | Liang Weijun Fu Yibing Chen Jianying |
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| Institution: | Liang Weijun,Fu Yibing,Chen Jianying.Department of Cardiology,Affiliated Hospital of Guangdong Medical College,Zhanjiang 524001 |
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| Abstract: | Objective To study the clinical significance of changes of plasma nitric oxide (NO) and tumor necrosis factor (TNF) levels in patients with congestive heart failure (CHF).Methods Plasma NO and TNF in 68 CHF cases were tested.30 healthy subjects served as normal controls.Results Plasma NO and TNF levels in CHF patients were obviously higher than those in normal subjects (P<0.01).The increase of NO and TNF levels was related to severity of CHF.Conclusion The increase of NO and TNF might be a pathophysiological characteristic of CHF,which can be used as an important index to judge the grading of cardiac function. |
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| Keywords: | Congestive heart failure Nitric oxide Tumor necrosis factor |
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