青年女性大肠癌的临床特点分析

目的 分析青年女性大肠癌的临床特点，提高对青年女性大肠癌的认识。方法 总结该院5年间收治的32例年龄低于35岁青年女性大肠癌内镜资料、临床表现、病理及原癌基因蛋白（c-erbB-2）表达和治疗情况，同期青年男性作对照。结果 青年女性大肠癌在内镜特征、临床表现和病理上与男性患者相似，血色素测定女性组明显低于男性组（P〈0．001）；c-erbB-2蛋白表达水平女性组高于男性纽（P〈0．05）。结论 贫血可能是提示青年女性大肠癌具有诊断价值的参考指标，检测c-erbB-2蛋白表达可提示预后指导临床治疗。

Clinic characteristic analysis of colorectal carcinoma in young females

Objective To analyze the clin ic characteristic of colorectal carcinoma in young females.Methods Thirty-two female patients with colorectal carcinoma under 35 years of ages w ere reviewed as to their endoscopes datum,clinic representation,pathology,expres sion of c-erbB-2 protein,and 3-year survival rate.Results Th e endoscopes datum,clinic representation and pathology of both groups showed no statistical difference,but the hemoglobin was lower in the female group( P<0.001) and the expression rate of c-erbB-2 protein was higher than that of male group(P<0.05).Conclusions Colorec tal carcinoma in young females might present with anemia that should be excluded in differentiate diagnose.Expression of c-erbB-2 protein might be used as a p rognostic marker for therapy.