Vaccination with hemagglutinin or neuraminidase DNA protects BALB/c mice against influenza virus infection in presence of maternal antibody |
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| Authors: | Jianjun Chen Fenghua Zhang Fang Fang Haiyan Chang Ze Chen |
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| Affiliation: | (1) College of Life Science, Hunan Normal University, Changsha, 410081, Hunan, China;(2) State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Science, Wuhan, 430071, Hubei, China;(3) Shanghai Institute of Biological Products, Shanghai, 200052, China |
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| Abstract: | ![]()
Background Maternal antibody is the major form of protection against disease in early life; however, its presence interferes with active immunization of offspring. In order to overcome the immunosuppression caused by maternal antibody, several immune strategies were explored in this paper using mouse model and influenza vaccines. |
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