| 近视与开角型青光眼关系的Meta分析 |
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| 引用本文： | 熊期,曾宪涛,蔡小军,李志良,李朝辉,李胜.近视与开角型青光眼关系的Meta分析[J].中国循证医学杂志,2014(5):618-624. |
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| 作者姓名： | 熊期 曾宪涛 蔡小军 李志良 李朝辉 李胜 |
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| 作者单位： | [1]武汉大学第二临床学院,武汉430071 [2]武汉大学中南医院眼科,武汉430071 [3]湖北医药学院附属太和医院循证医学中心,湖北十堰442000 [4]华中科技大学同济医学院附属协和医院骨科,武汉430022 [5]武汉大学中南医院泌尿外科,武汉430071 |
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| 基金项目： | 湖北省科技厅面上项目（编号：2012FFB04324） |
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| 摘 要： | 目的系统评价近视与开角型青光眼(OGA)的相关性。方法计算机检索PubMed、EMbase、WanFang Data、VIP和CNKI数据库,收集国内外2000年1月~2013年5月公开发表的近视与OGA相关性的观察性研究。由2位研究者按照纳入与排除标准独立筛选文献、提取资料并评价纳入研究的方法学质量后,采用Stata 12.0软件进行Meta分析。结果最终纳入11个横断面研究,共45?996例患者。Meta分析结果显示:近视会增加罹患OGA的风险OR=1.91,95%CI(1.53,2.38)]。按照近视程度行亚组分析,结果显示低度近视(>–3.00 D)与中、高度近视(≤–3.00 D)发生OGA的风险分别为1.52倍OR=1.52,95%CI(1.23,1.88)]和2.41倍OR=2.41,95%CI(1.91,3.03)]。结论近视会增加OGA的发病风险。
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| 关 键 词： | 近视 开角型青光眼 系统评价 Meta分析 横断面研究 |
Association between Myopia and Open-angle Glaucoma： A Meta-Analysis |
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| XIONG Qi,ZENG Xian-tao,CAI Xiao-jun,LI Zhi-liang,LI Zhao-hui,LI Sheng.Association between Myopia and Open-angle Glaucoma： A Meta-Analysis[J].Chinese Journal of Evidence-based Medicine,2014(5):618-624. |
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| Authors: | XIONG Qi ZENG Xian-tao CAI Xiao-jun LI Zhi-liang LI Zhao-hui LI Sheng |
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| Institution: | 1. The Second Clinical College of Wuhan University, Wuhan 430071, China; 2. Department of Ophthalmology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China; 3. Center for Evidence-Based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, China; 4. Depariment of Orthpedics, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; 5. Department of Urology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China) |
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| Abstract: | Objective To systematically review the association between myopia and open-angle glaucoma （OAG）. Methods Foreign and domestic articles published from January 2000 to May 2013 were searched in PubMed, EMbase, WanFang Data, VIP and CNKI for observational studies on the association between myopia and OAG. According to the inclusion and exclusion criteria, the studies were screened, the data were extracted, and the method quality of included studies was assessed. Then meta-analysis was performed using Stata 12.0 software. Results Eleven cross-sectional studies including 45 996 participants were finally included. The results of meta-analysis showed that, myopia increased the risk of OAG. Besides, the results of subgroup analysis by the severity of myopia showed that, low-degree myopia （more than -3.00 D） increased 1.52 times the risk （OR=1.52, 95%CI 1.23 to 1.88） while middle/high-degree myopia （no more than -3.00 D） increased 2.41 times （OR=2.41, 95%CI 1.91 to 3.03）. Conclusion Individuals with myopia have increased risk of OAG |
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| Keywords: | Myopia Open-angle glaucoma Systematic review Meta-analysis Cross-sectional study |
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