婴幼儿轮状病毒肠炎合并多器管损害临床分析

目的 探讨婴幼儿轮状病毒肠炎合并心肌及肝脏、肾脏功能损害的发生情况.方法 将160例腹泻患儿根据病原学检测结果分为两组,观察组为婴幼儿轮状病毒肠炎患儿90例,对照组为非轮状病毒感染患儿70例,入院后分别进行血清cTnⅠ、ALT、AST、Cr、BUN、CK-MB及β2-MG测定,比较两组患儿心肌、肝脏、肾脏损害发生率,并比较观察组不同月龄和不同脱水程度患儿心肌、肝脏、肾脏损害发生率.结果 观察组患儿cTnⅠ、ALT、CK-MB、AST检测值高于对照组（P＜0.05）,BUN、Cr和β2-MG检测值与对照组比较差异无统计学意义（P＞0.05）;观察组患儿心肌损害、肝脏损害发生率高于对照组（P＜0.05）,肾脏损害与对照组比较差异无统计学意义（P＞0.05）;观察组中＜12个月患儿心肌损害、肝脏损害发生率高于＞12个月患儿（P＜0.05）;观察组中,重度脱水患儿心肌、肝脏、肾脏损害发生率均高于轻度脱水患儿（P＜0.05）.结论 婴幼儿轮状病毒肠炎可能导致心肌、肝脏及肾脏的损害,发生率与患儿月龄及脱水情况有一定关系.

Clinical analysis of rotavirus enteritis complicated with myocardial,liver and kidney damage in infants

Objective To investigate the occurrence of rotavirus enteritis complicated with myocardial and liver,kidney function damage in infants.Methods 160 diarrhea children were divided into two groups according to the results of pathogen result.90 children of rotavirus enteritis were in the observation group.70 children of non-rotaviral enteritis were in the control group.The serum cTnⅠ,ALT,AST,Cr,BUN,CK-MB and β 2-MG were determined.The incidence damage in myoeardium,liver and kidney were observed.Results ALT,CK-MB,AST of the observation group were higher than that of the control group：（P＜0.05）.BUN,Cr and β 2-MG of the control group was not significant different from that of the observation group （P＞0.05）.The incidence of myocardium and liver damage in infants of the observation group was higher than that of the control group （P＜0.05）.The myocardium and liver damage of infants less than 12 months of age in the observation group was higher than that of the infants more than 12 months of age （P＜ 0.05）.The incidence of myocardium,liver and kidney damage of the infants with severe dehydration in the observation group was higher than that of the infants with mild dehydration （P＜0.05）.Conclusion Rotavirus enteritis in infants may lead to myocardium,liver and kidney damage,whose incidence is related to the month of age and the dehydration.