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In vivo confocal microscopic findings of interlamellar stromal keratopathy induced by elevated intraocular pressure
Authors:Kurian Mathew  Shetty Rohit  Shetty Bhujang K  Devi Sathi A V
Affiliation:1. Instituto Federal de Educação, Ciência e Tecnologia de Brasília - IFB, Campus Planaltina, 73.380-900 Planaltina, DF, Brazil;2. Grupo ETCO, Departamento de Zootecnia, Faculdade de Ciências Agrárias e Veterinárias, UNESP, 14.884-900, Jaboticabal, SP, Brazil;3. Departamento de Economia, Sociologia e Tecnologia, Faculdade de Ciências Agronômicas de Botucatu, UNESP, 18.610-307, Botucatu, SP, Brazil;4. Agriculture and Agri-Food Canada, 2000 College Street, J1M 0C8 Sherbrooke, Quebec, Canada;5. Royal Veterinary College, University of London, London, United Kingdom
Abstract:
We report the confocal microscopic findings in a case of interlamellar stromal keratopathy induced by elevated intraocular pressure (IOP) after laser in situ keratomileusis (LASIK). In vivo confocal microscopy showed swollen and enlarged cellular structures and the presence of microlacunae separating the stromal collagen lamellae. Inflammatory mononuclear cells and granulocytes typically seen in patients with diffuse lamellar keratitis (DLK) were absent. Stopping the topical steroids with concurrent lowering of the IOP resulted in improvement in the uncorrected and best corrected visual acuities and was associated with resolution of the corneal findings. In vivo confocal microscopy is a useful tool to study interlamellar stromal keratopathy induced by elevated IOP after LASIK in humans and the response to treatment and to differentiate interlamellar stromal keratopathy from DLK.
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