新生儿淋菌性结膜炎致病菌10年药物敏感性的变迁

目的对2001年至2010年临床确诊的新生儿淋菌性结膜炎的病人结膜囊分泌物进行细菌培养和药物敏感性试验,探讨其致病菌药物敏感性10年的变迁,为临床合理用药提供依据。方法对78例临床诊断为新生儿淋菌性结膜炎患儿的结膜囊分泌物标本进行细菌培养,对培养出的淋球菌进行药物敏感性试验,并对数据进行分析。结果 10年来,新生儿淋菌性结膜炎的致病菌——淋球菌对头孢哌酮、头孢唑啉、环丙沙星和妥布霉素的药物敏感性高,对利福平、新霉素、氯霉素的耐药性强。结论新生儿淋菌性结膜炎首选环丙沙星眼药水和妥布霉素眼药水。病情严重者可以联合头孢哌酮或者头孢唑啉类的药物,同时应及早取标本进行细菌培养和药物敏感试验,以便在试验结果出来之后,及时修改治疗方案,以取得更好的临床效果。

The transition of drug sensitivity of neonatal gonococcal conjunctivitis in recent 10 years

Objective To study the results of drug sensitivity of Neisseria gonorrhoeae from the inferior palpebral conjunctival surface of neonate with gonocaccal cterial conjunctivitis and research the transition of drug sensitivity in recent 10 years.For clinical treatment and rational drug use,provide the basis.Methods Neisseria gonorrhoeae cultivated of conjunctival secretions of 78 cases with neonatal gonococcal conjunctivitis were drug sensitivity testing,and data analysis.Results The drug sensitivity of neonata...