| 阿扎司琼与恩丹西酮预防化疗性恶心呕吐的对照研究 |
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| 引用本文： | 孙亚红,张宝轩,郭其森,张燕,冯斌,范开席. 阿扎司琼与恩丹西酮预防化疗性恶心呕吐的对照研究[J]. 临床肿瘤学杂志, 2004, 9(1): 41-43 |
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| 作者姓名： | 孙亚红 张宝轩 郭其森 张燕 冯斌 范开席 |
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| 作者单位： | 250117,济南,山东省肿瘤医院内二科;250117,济南,山东省肿瘤医院内二科;250117,济南,山东省肿瘤医院内二科;250117,济南,山东省肿瘤医院内二科;250117,济南,山东省肿瘤医院内二科;250117,济南,山东省肿瘤医院内二科 |
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| 摘 要： | 目的 :比较阿扎司琼和恩丹西酮对预防恶性肿瘤化疗性呕吐的临床疗效。方法 :35例患者分为阿扎司琼组(A组 )和恩丹西酮组 (B组 )。阿扎司琼组 13例 ,化疗前静脉推注阿扎司琼 10mg ,隔日应用 1次 ;恩丹西酮组 2 2例 ,化疗前静脉推注恩丹西酮 8mg,每日 1次。结果 :阿扎司琼和恩丹西酮止吐的总有效率相近 (76 9%和 72 7% ) ,两组对比无明显差异 (P>0 0 5 ) ;但完全控制率分别为 5 3 8%和 4 0 9% ,两组比较差异有显著性 (P <0 0 5 )。对平均呕吐次数和初次呕吐时间也进行了比较 ,阿扎司琼和恩丹西酮有显著性差异 (P <0 0 5 )。结论 :阿扎司琼是一种预防化疗所致恶心呕吐的高效药物 ,不良反应很轻
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| 关 键 词： | 止吐剂 化学治疗 阿扎司琼 恩丹西酮 |
| 文章编号： | 1009-0460(2004)01-0041-03 |
| 修稿时间： | 2003-03-06 |
The Effect of Ondansetron and Azasetron was Compared in Prevention of Nausea and Vomiting Induced by Anti-Cancer Drugs |
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| SUN Ya-hong,ZHANG Bao-xuan,GUO Qi-sen,et al.. The Effect of Ondansetron and Azasetron was Compared in Prevention of Nausea and Vomiting Induced by Anti-Cancer Drugs[J]. Chinese Clinical Oncology, 2004, 9(1): 41-43 |
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| Authors: | SUN Ya-hong ZHANG Bao-xuan GUO Qi-sen et al. |
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| Affiliation: | SUN Ya-hong,ZHANG Bao-xuan,GUO Qi-sen,et al. Department of Medical Oncology,ShanDong Tumor Hospital,Jinan 250117 |
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| Abstract: | Objective:To study the efficacy of Azasetron in prevention of nausea and vomiting induced by anti-cancer drugs.Methods:35 patients were divided into two groups (group A and group B). Azasetron and Ondansetron were given separately to these two groups. Results:There was no significant difference between the Azasetron and Ondansetron, the effective rates were 84 6% and 77 6%. The completely response rates of two groups were 61 5% and 45 8% respectively (P<0 05). Conclusion:Azasetron is an active anti-emetic drug in prevention of nausea and vomiting induced by anti-tumor agents and its adverse reactions are mild. |
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| Keywords: | Anti-emetics Chemotherapy Azasetron Ondansetron |
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