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A case of polycythemia vera complicated by chronic renal failure under hemodialysis requiring parathyroidectomy for secondary hyperparathyroidisim
Authors:Seishi Inoue  Tadayasu Shono  Mieko Shono  Masayuki Azuma  Toshiaki Hirabayashi  Oshi Inagaki  Hidetaro Mori  Yoshikazu Fujita
Institution:(1) Dialysis Unit, Hyogo College of Medicine, 1-1, Mukogawa-Cho, 663 Nishinomiya, Hyogo, Japan
Abstract:A case of polycythemia vera complicated by chronic renal failure under maintenance hemodialysis requiring parathyroidectory (PTH) for secondary hyperparathyroidism (2° HPT) is reported. A 62 year old female presented with 75000 white blood cells (WBC)/μl, 703×104 red blood cells (RBC)/μl, 23×104 platelets (PLT)/μl, hyperuricemia and hypertension in 1970 and the diagnosis of polycythemia vera was made. Hemodialysis was started in October 1974 for chronic renal failure. Blood cells in peripheral blood rapidly decreased in number after the beginning of dialysis, reaching the level of 10000∼20000 WBC/μl, and 150∼250×104RBC/μl. In August 1988, marked bone resorption in X-ray picture and high serum alkaline phosphatase and parathyroid hormone (PTH) noted along with 17400 WBC/μl, 370×104RBC/μl and 35.9×104PLT/μl.
Keywords:Polycythemia vera  Secondary Hyperparathyroidism  Hemodialysis  Parathyroid hormone (PTH)  Uremic toxin
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