多原发恶性肿瘤19例分析

目的：探讨胃肠道多原发恶性肿瘤的临床特点。方法：通过病案管理系统检索我院近22a手术治疗的恶性肿瘤1460例，其中19例经病理确诊为多原发恶性肿瘤，发生率为1．3％。男女之比为1：1．8。结果：同时性恶性肿瘤4例，异时性恶性肿瘤15例；同时性恶性肿瘤经手术治疗预后与单发恶性肿瘤相似，而异时性恶性肿瘤预后好于单发恶性肿瘤。这些对癌症普查及手术治疗都有指导作用。结论：上述研究对阐明多原发恶性肿瘤的发生机制、提高患5a生存率有重要意义。

An analysis of 19 cases of multiple primary maligant neoplasms

Objective: To explore the clinical features of multiple primary maligant neoplasms. Methods: In the past 20 years 1460 cases of maligant neoplasms were surgically treated in Tianjin Soda Plant Hospital. Muliple primary maligant neoplasms were pathologieally confirmed in 19 (1.3%) of these patients. Ratio of male to female was 1:1.8. Results: In these 19 cases, the tumors of 4 cases were synchronous and 15 cases wene metachronous. Survival rate in patients with synchronous tumor were similar to that in patients with single tumor. However patients with metachronous tumor had better prognosis than those with single tumor. Conclusion: Multiple primary maligant neoplasms must be detected as early as possible. Early detection and excision may increase the 5 year survival rate.