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Analgesic adherence measurement in cancer patients: comparison between electronic monitoring and diary
Authors:Oldenmenger Wendy H  Echteld Michael A  de Wit Rianne  Sillevis Smitt Peter A E  Stronks Dirk L  Stoter Gerrit  van der Rijt Carin C D
Institution:

aDepartment of Medical Oncology, Erasmus Medical Center, Rotterdam

bDepartment of Pain Expertise Center, Erasmus Medical Center, Rotterdam

cDepartment of Medical Psychology and Psychotherapy, Erasmus Medical Center, Rotterdam

dDepartment of Neurology, Erasmus Medical Center, Rotterdam

eInstitute for Research in Extramural Medicine, VU University Medical Center, Amsterdam

fSection of Nursing Science, University of Maastricht, The Netherlands

gNursing Faculty, University Hospital Maastricht, Maastricht, The Netherlands

Abstract:Adherence to analgesics in cancer patients has scarcely been studied. In this study, the Medication Event Monitoring System (MEMS) and medication diaries were compared with respect to feasibility and adherence measurements. Forty-six outpatients with nociceptive pain caused by cancer were asked to use MEMS for their analgesics and to record their medication usage in a diary for four weeks. Seventy-nine percent of the patients used MEMS for the full four-week period; 70% did so for the diary. The majority of patients were satisfied with both MEMS and diary. Adherence data assessed by MEMS and diary were comparable. Patients used the amount of analgesics adequately (taking adherence: 87%) but took them irregularly (timing adherence: 53%). Subgroup analyses in patients using single and multiple analgesic regimens confirmed the comparable suitability of both methods. MEMS and a medication diary are equally useful for analgesic adherence measurement in cancer patients with pain.
Keywords:Cancer pain  adherence  electronic measurement  diary  analgesics
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