Postmortem pathology of opportunistic infection in a HIV positive patient--a case report

An autopsy case of HIV positive patient with multiple opportunistic infections is described. We received heart, lungs, spleen and both the kidneys along with pieces of cerebrum for anatomy and histopathological examination. Histology of organs revealed disseminated non-granulomatous necrotizing type of tissue reaction with superadded infection with Cryptococcus neoformans (C. neoformans) in liver and brain. Pneumocysts carini (P. carini) induced pneumonia in lungs, disseminated mycobacterial infection in spleen, lungs, liver and kidneys and acute fibrinous meningitis with superadded infection with C. neoformans in brain. Special stains were carried out to demonstrate different organisms.