GABA(A)/central benzodiazepine receptor and peripheral benzodiazepine receptor ligands as inducers of phenobarbital-inducible CYP2B and CYP3A |
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| Authors: | Roberge Christian Beaudet Marie-Josée Anderson Alan |
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| Affiliation: | Centre de Recherche de l'H?tel-Dieu de Québec, Québec, Canada G1R2J6. |
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| Abstract: | ![]()
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| Keywords: | CAR, constitutively active receptor or constitutive androstane receptor DMSO, dimethylsulfoxide FGIN 1-27, N,N-dihexyl-2-(4-fluorophenyl)indole-3-acetamide GABA, γ-aminobutyric acid GAPDH, glyceraldehyde phosphate dehydrogenase PB, phenobarbital PBR, peripheral benzodiazepine receptor PBRU, phenobarbital response unit PK 11195, 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide PVDF, polyvinylidene difluoride PXR, pregnane X receptor Ro5-4864, 4′-chlorodiazepam SDS, sodium dodecyl sulphate DCPPBT, 7-(dimethylcarbamoyloxy)-6-phenylpyrrolo-[2,1-d][1,5]benzothiazepine DBI/ACBP, diazepam binding inhibitor/acyl-CoA binding protein |
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