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一种针刺补泻法对小型猪皮下组织液压的影响
引用本文:李宏彦,贾术永,王广军,宋晓晶,叶丰瑶,顾鑫,熊枫,王燕平,张维波.一种针刺补泻法对小型猪皮下组织液压的影响[J].医用生物力学,2020,35(2):228-234.
作者姓名:李宏彦  贾术永  王广军  宋晓晶  叶丰瑶  顾鑫  熊枫  王燕平  张维波
作者单位:中国中医科学院 针灸研究所,中国中医科学院 针灸研究所,中国中医科学院 针灸研究所,中国中医科学院 针灸研究所,北京中医药大学 针灸推拿学院,中国中医科学院 针灸研究所,中国中医科学院 针灸研究所,北京中医药大学 针灸推拿学院,中国中医科学院 针灸研究所
基金项目:国家自然科学基金项目(81173206)
摘    要:目的研究《灵枢》卷首《九针十二原》针刺补泻法对小型猪皮下组织液压(interstitial fluid pressure,IFP)的作用,探讨其调节组织液的生物力学机制。方法在9只健康实验用小型猪腹部随机取点行补法(提/按法)和泻法(摇大针孔),观察正常状态(normal state,NS)、抽取组织液的低组织液量(low volume,LV)状态和注入生理盐水的高组织液量(high volume,HV)状态下针刺前后IFP。结果 NS下提/按法可极显著升高IFP;泻法可极显著降低IFP,针后5 min泻法组IFP降低较快。LV状态提/按法均能升高IFP,针后10 min二者IFP下降较慢。HV状态下泻法可极显著降低IFP,针后5 min与对照组变化趋势不同。结论该补泻法可升高或降低IFP,证明其对IFP有相反方向的调节作用。研究结果为针灸临床使用补泻手法提供新的科学依据。

关 键 词:针刺    补泻手法    组织液    组织液压
收稿时间:2019/3/25 0:00:00
修稿时间:2019/5/13 0:00:00

Effects of a Reinforcing and Reducing Method of Acupuncture on Interstitial Fluid Pressure in Subcutaneous Tissue of Minipig
LI Hongyan,JIA Shuyong,WANG Guangjun,SONG Xiaojing,YE Fengyao,GU Xin,XIONG Feng,WANG Yanping,ZHANG Weibo.Effects of a Reinforcing and Reducing Method of Acupuncture on Interstitial Fluid Pressure in Subcutaneous Tissue of Minipig[J].Journal of Medical Biomechanics,2020,35(2):228-234.
Authors:LI Hongyan  JIA Shuyong  WANG Guangjun  SONG Xiaojing  YE Fengyao  GU Xin  XIONG Feng  WANG Yanping  ZHANG Weibo
Institution:Institute of Acu-Moxibustion, China Academy of Chinese Medical Sciences,Institute of Acu-Moxibustion, China Academy of Chinese Medical Sciences,Institute of Acu-Moxibustion, China Academy of Chinese Medical Sciences,Institute of Acu-Moxibustion, China Academy of Chinese Medical Sciences,School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine,Institute of Acu-Moxibustion, China Academy of Chinese Medical Sciences,Institute of Acu-Moxibustion, China Academy of Chinese Medical Sciences,School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine and Institute of Acu-Moxibustion, China Academy of Chinese Medical Sciences
Abstract:Objective To study the effect of the reinforcing and reducing method of acupuncture reported in first Chapter the Nine Needles and Twelve Yuan of the Miraculous Pivot on interstitial fluid pressure (IFP) in subcutaneous tissue of minipig, and to investigate its biomechanical mechanism of regulating the interstitial fluid. Methods Nine healthy minipigs were randomly selected for reinforcing method (pull or press) and reducing method (wave a big pinhole), and tested on soft skin tissues of the abdomen. The IFP in the normal state (NS), the low volume (LV) state (by extracting interstitial fluid) and the high volume (HV) state (by injecting saline solution) was measured before and after acupuncture. Results In the normal state, pulling and pressing the needle could obviously increase IFP, while reducing method could significantly decrease IFP, leading to a rapid decrease in 5 min after acupuncture. In the LV state, pulling and pressing the needle could increase IFP. However, in 10 min after acupuncture, the descend rates of IFP were relatively slower. In the HV state, the reducing method could significantly decrease IFP, and the changing trend in 5 min after acupuncture was different from that of the control group. Conclusions The reinforcing and reducing method of acupuncture could increase or decrease IFP, which proved that the acupuncture method could regulate IFP in the opposite direction. The research findings provide a new scientific basis for using reinforcing and reducing method of acupuncture in clinic.
Keywords:acupuncture  reinforcing and reducing method of acupuncture  interstitial fluid  interstitial fluid pressure (IFP)
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