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Re-examining the role of adjuvant radiation therapy |
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| Authors: | Andrew Spillane BMedSci BMBS MD FRACS Angela Hong MBBS PhD FRANZCR (FRO) Gerald Fogarty BSc MBBS PhD FRANZCR |
| Affiliation: | 1. Surgical Oncology, Northern Clinical School, The University of Sydney, Sydney, Australia;2. Surgical Oncology, Northern Clinical School, The University of Sydney, Sydney, Australia Melanoma Institute Australia, Sydney, Australia Melanoma Unit, Mater Hospital, Sydney, Australia Radiation Oncology, Royal Prince Alfred Hospital, Sydney, Australia Radiation Oncology, GenesisCare, Mater Radiation Oncology, Sydney, Australia;3. Surgical Oncology, Northern Clinical School, The University of Sydney, Sydney, Australia Melanoma Institute Australia, Sydney, Australia Melanoma Unit, Mater Hospital, Sydney, Australia Radiation Oncology, St Vincents Hospital, Sydney, Australia Radiation Oncology, GenesisCare, Mater Radiation Oncology, Sydney, Australia |
| Abstract: | Previously important roles for adjuvant radiotherapy (RT) in melanoma patients included improved regional control after resection of high-risk nodal disease, to reduce local recurrence for desmoplastic, and other subtypes of melanoma with neurotropism, reducing in-brain relapse of brain metastases after surgery and other situations on a case-by-case basis. This review evaluates the integration of adjuvant RT into clinical practice at this time of rapidly evolving knowledge and improving outcomes from effective systemic therapy. |
| Keywords: | adjuvant radiotherapy effective systemic therapy melanoma regional lymph node dissection |