3 245例新生儿早产危险因素研究

目的：探讨新生儿早产的危险因素，为预防和控制早产提供科学依据。方法：收集1994－1998年在广西医科大学第一附属医院妇产科住院分娩的3245例新生及其母亲有关资料，采用非条件Logistic回归模型分析与早产有关的因素。结果：在纳入研究的3245例新生儿中，早产儿225例，发生率为6．93％；与早产发生有关的因素是：胎儿畸形（b=3.144,OR=23.19）、多胎妊娠（b=2.497,OR=12.14）、胎膜早破（b=0.827,OR=2.29）、产次(b=0.281,OR=1.33)、母亲职业（b=0.384,OR=1.47)、脐带长度（b=-0.037,OR=0.96)、产检查次数（b=-0.198,OR=0.82）。结论：胎儿畸形，多胎妊娠，胎膜早破，脐带过短、产次越多以及母亲职业是农民等因素能增加新生儿早产的危险性，而进行产前检查会降低早产的危险性。

The Study on the Risk Factors of Preterm Birth of 3 245 Newborn

OBJECTIVE To investigate the risk factors association with preterm birth of newborn,and to provide scientific basis for preventing and control the occurring of pretrm birth. METHODS 3 245 infants born in the first affiliated hospital of Guangxi Medical University during 1994-1998 and the pregnant women were studied. The data obtained from the infants and their mothers was analyzed for the risk factors of preterm birth by utilizing logistic regression model. RESULTS Among 3 245 newborn,225 were preterm birth,The incidence rate is 6.93% .The factors related to preterm birth were:Congenital malformation of fetus(b = 3.144,OR = 23.19), multiple-gestation pregnancy(b= 2.497,OR = 12.14), premature rupture of membrance(b = 0.827,OR = 2.29), times of delivery! b = 0.281, OR = 1.33), occupation of pregnant women(b= 0.384,OR= 1.47) .length of umbilical cord(b= -0.037,OR= 0.%) .times of antenatal examinationb= - 0.198,OR=0.82). CONCLUSION Premature delivery associationwith multiple factors, Congenital malformation of fetus, multiple-gestation pregnancy, premature rupture of membrance.the short umbilical cord,more delivery and boorish pregnant women were risk factors. Whereas,regular antenatal care was protective factor.