| 微炎症状态对慢性肾功能衰竭非透析患者肾功能影响的研究 |
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| 引用本文： | 王鸿泰,李秀珍,李捷. 微炎症状态对慢性肾功能衰竭非透析患者肾功能影响的研究[J]. 现代中西医结合杂志, 2007, 16(22): 3131-3132 |
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| 作者姓名： | 王鸿泰 李秀珍 李捷 |
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| 作者单位： | 山东省聊城市人民医院,山东,聊城,252000 |
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| 摘 要： | 目的探讨慢性肾功能衰竭(CRF)非透析患者微炎症状态对肾功能的影响。方法选择CRF CKD分期Ⅲ~Ⅳ期非透析患者150例,采用ELISA方法测定血清白细胞介素-6(IL-6)、肿瘤坏死因子(TNF-α)的浓度,用免疫速率比浊法测定C-反应蛋白(CRF)的浓度并根据其浓度分为微炎症状态组(56例)和非微炎症状态组(94例),观察2组患者3个月后肾功能水平。结果微炎症状态组较非微炎症状态组肾功能下降明显。结论CRF非透析患者微炎症状态对肾功能有负面影响,控制微炎症状态对CRF有益。
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| 关 键 词： | 慢性肾功能衰竭 非透析 微炎症 |
| 文章编号： | 1008-8849（2007）22-3131-02 |
| 收稿时间： | 2006-08-30 |
| 修稿时间： | 2006-08-30 |
Study of the effect of microinflammation on the renal function in non-dialysis patients with chronic renal failure |
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| WANG Hong-tai,LI Xiu-zhen,LI Jie. Study of the effect of microinflammation on the renal function in non-dialysis patients with chronic renal failure[J]. Modern Journal of Integrated Chinese Traditional and Western Medicine, 2007, 16(22): 3131-3132 |
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| Authors: | WANG Hong-tai LI Xiu-zhen LI Jie |
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| Abstract: | Objective It is to explore the effect of microinflammation on the renal function in non-dialysis patients with chronic renal failure(CRF).Methods 150 non-dialysis patients with CRF in Ⅲ-Ⅳ stage staging by CKD were chosen,and contents of serum IL-6,TNF-ɑ in them were measured with ELISA and CRF with immunoturbidimetry.All the patients were divided into microinflammation group(56 cases) and non-microinflammation group(94 cases),and their renal functions after 3 months were observed.Results The renal function in microinflammation group was worse than that in non-microinflammation group.Conclusion Microinflammation has a negative effect on renal function in non-dialysis patients with CRF,so controlling it is benefit to the patients. |
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| Keywords: | chronic renal failure non-dialysis microinflammation |
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