|
|||||
|
|
| IVF失败者子宫内膜galectin-3表达及其容受性评估 | |
| 引用本文： | 赵世彬,甄秀丽,孙海茹,张娜,乜照燕,张轶. IVF失败者子宫内膜galectin-3表达及其容受性评估[J]. 山东医药, 2011, 51(24): 36-38 |
| 作者姓名： | 赵世彬 甄秀丽 孙海茹 张娜 乜照燕 张轶 |
| 作者单位： | 1. 河北医科大学第四医院,石家庄,050011 2. 衡水哈励逊国际和平医院 |
| 基金项目： | 河北省科学技术研究与发展计划项目,河北省计生委科研项目 |
| 摘 要： | 目的以子宫内膜着床窗口期galectin-3表达评价体外受精—胚胎移植（IVF）失败者子宫内膜容受性。方法对IVF失败者11例的前一月经周期着床窗口期子宫内膜采用逆转录PCR技术检测子宫内膜galectin-3 mR-NA表达和免疫组化检测子宫内膜galectin-3蛋白表达及定位。结果IVF失败者子宫内膜着床窗口期galectin-3的表达明显低于妊娠组。结论IVF失败患者着床窗口期子宫内膜容受性欠佳,胚胎着床障碍是主要原因之一。 |
| 关 键 词： | galectin-3 受精,体外 子宫内膜容受性 |
Expression of galectin-3 in windows phase evaluating the IVF-loser's endometrial receptivity |
|
| ZHAO Shi-bin,ZHEN Xiu-li,SUN Hai-ru,ZHANG Na,NIE Zhao-yan,ZHANG Yi. Expression of galectin-3 in windows phase evaluating the IVF-loser's endometrial receptivity[J]. Shandong Medical Journal, 2011, 51(24): 36-38 | |
| Authors: | ZHAO Shi-bin ZHEN Xiu-li SUN Hai-ru ZHANG Na NIE Zhao-yan ZHANG Yi |
| Affiliation: | ZHAO Shi-bin1,ZHEN Xiu-li,SUN Hai-ru,ZHANG Na,NIE Zhao-yan,ZHANG Yi(1 The Forth Hospital of Hebei Medical University,Shijiazhuang 050011,P.R.China) |
| Abstract: | Objective To evaluate in vitro fertilization(IVF)-loser's endometrial receptivity by investigating the expression of galectin-3 in windows phase.Methods The mRNA expression of galectin-3 was detected by RT-PCR method.Immunohistochemistry was used to detect the location and the expression of galectin-3 protein.Result Galectin-3 mRNA and protein expression in the non-pregnant group were obviously lower than those in the prengant group.Conclusion IVF-loser's endometrial receptivity is not good in implantation ... |
| Keywords: | galectin-3 fertilization in vitro endometrial receptivity |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |