Human monocyte antigens in a random sample from Japan. |
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Authors: | T Nagai Y Sugita M Kurihara T Ikeda M Rose |
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Institution: | Department of Hemogenetics, Kitasato University School of Hygienic Sciences, Sagamihara-shi, Japan. |
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Abstract: | We studied a random sample of Japanese and compared both Japanese and German monocyte antigen frequencies and performed a segregation analysis in Japanese families. In Japanese, the following gene frequencies were established: 0.1033 for HMA-A1; 0.0299 for HMA-A3; 0.0033 for HMA-A6; 0.1521 for HMA-B2. Data on the gene frequency in Germans were presented by Rose. In this comparison, the frequency for HMA-B2 in Japanese is more than two times higher; for antigen HMA-A6, the Japanese is a fifth of the German quantity. The antigen HMA-B4 was not found in Japanese. The results we obtained from family analysis confirmed an unambiguous autosomal, codominant inheritance of the examined HMA antigens. |
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