临床分离铜绿假单胞菌感染及耐药性分析

目的研究临床铜绿假单胞菌感染的科室分布和菌株耐药情况。方法收集2006年01月至2007年12月期间，临床分离的铜绿假单胞菌1947株，经过VITEK-32全自动微生物分析系统或API20NE非肠道革兰氏阴性杆菌鉴定系统的鉴定，然后采用VITEK-32分析系统或者ATBPSE-5，以及K-B法进行药敏测定，并分析其病例资料。结果铜绿假单胞菌引起的感染主要发生在呼吸科、ICU、泌尿科、神经内科；铜绿假单胞菌对常用17种抗茵药物的耐药率除多粘菌素E耐药率略为下降外，其它均增高。结论2007年相较2006年度铜绿假单胞菌感染率与耐药性均呈现上升趋势，以呼吸科和ICU最为常见。

Analysis of pseudomonsa aeruginosa related infection and drug-resistance

Objective The aim of this research was to investigate infection distribution and drug-resistance of Pseudomonsa aeruginosa. Methods 1947 clinical Pseudomonsa aeruginosa strains were separated from The Third People Hospital of Chengdu from January 2006 to December 2007. VITEK-32 fully-automatic microbial analysis system or bioMerieux Api 20NE non-intestinal gram-negative bacilli identification system were used to identify the bacillus. Then the sensitivity of antibiotics test of these strains were detected with VITEK-32fully-automatie microbial analysis system or ATB PSE-5 as well as K-B method. Results Infection with Pseudomonsa aeruginosa were mainly at respiratory medicine, intensive care unit, department of urology and department of internal neurology. The drug-resistance rate of Pseudomonsa aeruginosa to many agents increased except Polymyxin E. Conclusion The drug-resistance and infection rate of Pseudomonsa aeruginos in 2007 were higher than that in 2006.