| 培菲康佐治小儿反复呼吸道感染的临床观察 |
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| 引用本文： | 佘志婉,张新玲,薛立军.培菲康佐治小儿反复呼吸道感染的临床观察[J].实用全科医学,2010,8(3):319-320. |
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| 作者姓名： | 佘志婉 张新玲 薛立军 |
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| 作者单位： | 广东省深圳市宝安区松岗人民医院儿科,518000 |
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| 摘 要： | 目的探讨肠道菌群调节剂（培菲康）辅助治疗小儿反复呼吸道感染（RRI）的疗效，及其对T细胞亚群的影响。方法选择96例反复呼吸道感染的患儿，随机将患几分为两组，两组患儿急性期均给予常规治疗，治疗组在对照组常规治疗的基础上，加服培菲康，疗程为6个月。两组患儿均随访12个月，记录呼吸道感染情况、T细胞亚群（CD3、CD4、CD8）检测结果及不良反应。结果治疗组、对照组总有效率分别为91．3％、73．3％，总有效率比较差异有统计学意义（P〈0．05）。治疗组的呼吸道感染次数（t=9．09），发热天数（t=7．22）、咳嗽天数（t=7．58）均少于对照组，差异有统计学意义（P均〈0．01）；治疗组在治疗后的CD3、CD4、CD4／CD8比值均升高（P均〈0．01），CD8降低（P〈0．01）；对照组用药前、后CD3、CIM、CD8、CD4／CD8之值无显著性差异（P〉0．05）。结论培菲康对反复呼吸道感染患儿有免疫调节作用，对反复呼吸道感染急性发作可起到一定的预防作用。
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| 关 键 词： | 反复呼吸道感染 培菲康 免疫 小儿 |
Clinical Study on Supplementary Treating Recurrent Respiratory Tract Infection by Bifico |
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| SHE Zhi-wan,ZHANG Xin-ling,XUE Li-jun.Clinical Study on Supplementary Treating Recurrent Respiratory Tract Infection by Bifico[J].Applied Journal Of General Practice,2010,8(3):319-320. |
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| Authors: | SHE Zhi-wan ZHANG Xin-ling XUE Li-jun |
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| Institution: | SHE Zhi-wan,ZHANG Xin-ling,XUE Li-jun.Department of Pediatrics,Songgang People\'s Hospital of Baoan District in Shenzhen,Shenzhen 518000,Guangdong,China |
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| Abstract: | Objective To investigate the supplementary effect of Bifico on T lymphocyte subsets in children with recurrent respiratory tract infection.Methods 96 children with recurrent respiratory tract infection were randomly allocated into two groups:the treatment group received conventional treatment plus bifico and the control group received conventional treatment only.The episodes of RRI,the T lymphocyte subsets(CD3,CD4,CD8) measurements and the adverse events were recorded in the following 12 months.Results The ... |
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| Keywords: | Respiratory tract infection Bifico Immunity Children |
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