| 银杏叶中聚戊烯醇类化合物的分离纯化研究 |
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| 引用本文： | 李永辉,宿树兰,欧阳臻,杨克迪.银杏叶中聚戊烯醇类化合物的分离纯化研究[J].中药材,2004,27(5):337-339. |
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| 作者姓名： | 李永辉 宿树兰 欧阳臻 杨克迪 |
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| 作者单位： | 江苏大学制药工程系,镇江,212013 |
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| 基金项目： | 江苏省教育厅自然科学基金 |
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| 摘 要： | 目的:探讨银杏叶中聚戊烯醇类化合物的分离纯化方法.方法:以聚戊烯醇的纯度为指标,筛选冷冻脱杂和硅胶柱层析最佳条件,获得含量90%以上的提取物.先用160倍量的石油醚-乙酸乙酯(9:1)溶剂冷冻除杂,然后用硅胶柱层析进一步纯化(洗脱剂为石油醚-乙酸乙酯19:1).结果:精制后的聚戊烯醇纯度可达92.7%.结论:冷冻脱杂后再进行硅胶柱层析,可明显提高聚戊烯醇纯度,该方法重现性好,经济实惠,简单可靠.
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| 关 键 词： | 银杏 聚戊烯醇 |
| 修稿时间： | 2004年2月10日 |
Studies on Purification of Polyprenol from Ginkgo biloba L.Leaves |
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| Li Yonghui,Su Shulan,Ouyang Zhen,Yang Kedi.Studies on Purification of Polyprenol from Ginkgo biloba L.Leaves[J].Jorunal of Chinese Medicinal Materials,2004,27(5):337-339. |
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| Authors: | Li Yonghui Su Shulan Ouyang Zhen Yang Kedi |
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| Institution: | Department of Pharmaceutical Engineering of Jiangsu University, Zhenjiang 212013. |
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| Abstract: | OBJECTIVE: To research the methods of purifying polyprenol from leaves of Ginkgo biloba L.. METHODS: The purity of polyprenol was determined by HPLC to select the optimal purifying conditions. RESULTS: The optimal conditions were degreased by 160 times of petroleum ether-ethyl acetate (9:1) firstly, then through a silica gel column (100-140 mesh) and eluted with petroleum etherethyl acetate (19:1). CONCLUSION: The methods are feasible to purify polyprenol from leaves of Ginkgo biloba L. and could increase the purity of polyprenol obviously. |
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| Keywords: | Ginkgo biloba L Polyprenol |
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