前部缺血性视神经病变的吲哚青绿和 荧光素眼底血管造影

目的观察前部缺血性视神经病变( anterior isc hemic optic neuropathy , AION)的吲哚青绿和荧光素眼底血管造影(indocyanine green angiography and fundus fluorescein angiography ,ICGA &; FFA)特征，探讨AION的病因 和发病机制，以及ICGA和FFA在AION诊断和研究方面的价值。方法对比分析AION患者31例32只眼和非AION眼底病患者38例38只眼ICGA＆FFA同步检查的图 像以及AION患者的视野检查资料。结果AION组中视盘全部或 部分位于脉络膜血液供应分水带内的眼数显著多于非AION (P<0.005)；所有接受检查眼通过视盘的分水带都为垂直状，视盘两侧脉络膜血管充盈较上下方为快。AION 患者的分水带分型与视盘缺血部位存在明确的对应关系。ICGA早期视盘无荧光 ，晚期视盘缺血区均无荧光，非缺血区主要表现为不均匀荧光。结论AION的发病与盘周脉络膜血液供应状态有关。ICGA在对AION的诊断和研究方面比FFA 具有更大的价值。(中华眼底病杂志,2001,17:111-114)

Indocyanine green and fundus fluorescein angiography in anterior ischemic optic neuropathy

ObjectiveTo observe the characteristics of indocyanine green angiography and fundus fluorescein angiography (ICGA &; FFA) in anterior ischemic optic neuropathy ( AION ) , and to investigate the etiology of AION and the value of ICGA and FFA in the diagnosis and study of AION. MethodsSimultaneous ICGA and FFA were performed on 32 eyes of 31　AION patients and 38 eyes of 38 non-AION patients. ResultsThe eyes that all or a part of the optic disclies in the watershed zon es of the choroidal blood supply were significantly more in the AION group tha n those in the non-AION group (P< 0.005 ) . All the watershed zones through the optic disc were vertical in shape. The fluorescence filling of the inferior and superior choroidal blood vessels near the optic disc were all slower than that of the temporal and nasal choroidal blood vessels. The types of watershed zones in the AION group were highly correspondent to the ischemic areas of the optic disc . In early ICGA , no fluorescence appeared at the optic disc, and in later stage, the ischemic area revealed no fluorescence, and the other area showed mostly asymmetric fluorescence.ConclusionThe onset of AION is correlative to the choroidal blood supply around the optic disc. ICGA is more valuable in the diagnosis and study of AION than FFA .(Chin J Ocul Fundus Dis, 2001,17:111-114)