| 红葱的化学成分和生物活性研究 |
| |
| 引用本文： | 吴佳妮,陈德力,刘洋洋,郑传莉,贾飞龙,马国需,孙维红. 红葱的化学成分和生物活性研究[J]. 中草药, 2018, 49(13): 2967-2971 |
| |
| 作者姓名： | 吴佳妮 陈德力 刘洋洋 郑传莉 贾飞龙 马国需 孙维红 |
| |
| 作者单位： | 宁夏医科大学总医院药剂科;中国医学科学院北京协和医学院药用植物研究所海南分所 |
| |
| 基金项目： | 海南省重点研发计划（ZDYF2017127）；宁夏医科大学校级项目（XM2016093） |
| |
| 摘 要： | ![]()
目的研究红葱Eleutherine americana的化学成分。方法采用硅胶柱色谱、薄层色谱、Sephadex LH-20柱色谱、半制备高效液相色谱等方法进行分离纯化,通过理化性质及波谱数据鉴定化合物结构。结果从红葱中分离出15个化合物,分别鉴定为大根香叶烯B(1)、phaffiaol(2)、4,8-dihydroxy-3-methoxy-l-methylonthra-9,10-quinone-2-carboxylic acid methyl ester(3)、3-heptadecyl-5-methoxyphenol(4)、亚油酸乙酯(5)、3,5-dimethoxybiphenyl-4′-ol(6)、karwinaphthol A(7)、5-hydroxylkarwinaphthol A(8)、3,4-dimethoxy-8-hydroxy-1-methyl-anthra-9,10-quinone-2-carboxylic acid methyl ester(9)、异红葱乙素(10)、红葱乙素(11)、异红葱甲素(12)、naphtho-γ-lactone(+)-9-hydroxyeleutherol(13)、洋川芎醌(14)、棕榈油酸(15)。结论化合物2、4~7、13~15均为首次红葱属植物中分离得到,化合物3、8、13的舒张血管作用较强,舒张率分别达到了85.3%、81.8%、89.5%,基本与阳性药丹参酮IIA(86.3%)相当。
|
| 关 键 词： | 鸢尾科 红葱 血管舒张活性 红葱乙素 洋川芎醌 棕榈油酸 |
| 收稿时间： | 2018-01-23 |
Chemical constituents and bioactive activities of Eleutherine americana |
| |
| WU Jia-ni,CHEN De-li,LIU Yang-yang,ZHENG Chuan-li,JIA Fei-long,MA Guo-xu and SUN Wei-hong. Chemical constituents and bioactive activities of Eleutherine americana[J]. Chinese Traditional and Herbal Drugs, 2018, 49(13): 2967-2971 |
| |
| Authors: | WU Jia-ni CHEN De-li LIU Yang-yang ZHENG Chuan-li JIA Fei-long MA Guo-xu SUN Wei-hong |
| |
| Affiliation: | Department of Pharmacy, General Hosiptal of Ningxia Medical University, Yinchuan 750004, China,Hainan Branch of Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Wanning 571533, China,Hainan Branch of Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Wanning 571533, China,Department of Pharmacy, General Hosiptal of Ningxia Medical University, Yinchuan 750004, China,Department of Pharmacy, General Hosiptal of Ningxia Medical University, Yinchuan 750004, China,Hainan Branch of Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Wanning 571533, China and Department of Pharmacy, General Hosiptal of Ningxia Medical University, Yinchuan 750004, China |
| |
| Abstract: | ![]()
|
| |
| Keywords: | Iridacea Eleutherine americana Merr.et Heyne vasodilatation activity eleutherin senkyunone palmitoleic acid |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中草药》浏览原始摘要信息 |
|
点击此处可从《中草药》下载全文 |
|
