气相色谱串联质谱法同时测定黄芪中238种农药残留

 目的 采用气相色谱-串联质谱法建立黄芪中农药多残留的测定方法。方法 样品经改良后QuEChERS方法提取，采用氨丙基固相萃取小柱净化，并采用气相色谱-串联质谱同时定性、定量测定。结果 对黄芪进行了3个添加水平的回收实验，结果表明238种农药的回收率大多在70.0％～120.0％，相对标准偏差小于15％，检测限大多低于0.01 mg·kg^-1。结论 本法操作简单，净化效果好，灵敏度高，重现性好，可用于黄芪样品中农药多残留的日常检测。

Simultaneous Determination of 238 Pesticide Residues in Astrgalus membranaceus by GC-MS/MS

OBJECTIVE To study the multi-residues detection methods for Astrgalus membranaceus by GC-MS/MS.METHODS The extraction was performed by modified QuEChERS method,and then cleaned by PSA solid phase extraction(SPE) cartridge.The residue detection was carried out by GC-MS/MS,which could identify and quantify pesticide simultaneously.RESULTS The analytical performance was validated by recovery experiments that were fortified at three levels for each pesticide.In general,the recoveries ranged from 70% to 120% and the relative standard deviations(RSDs) were all less than 15%.The limits of detection(LODs) for most of the selected pesticides were below 0.01 mg·kg-1.CONCLUSION The method shows high sensitivity,good repeatability and satisfactory cleaning-up excellence,which could be applied to the pesticide residue detection for Astrgalus Membranaceus.