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硝苯地平缓释微丸的研制
引用本文:贺英菊,陈瑜,李丽萍,孙毅毅. 硝苯地平缓释微丸的研制[J]. 华西药学杂志, 1999, 14(3): 175-176
作者姓名:贺英菊  陈瑜  李丽萍  孙毅毅
作者单位:1. 华西医科大学药学院,成都,610041
2. 深圳中联广深医药股份有限公司,深圳,518029
摘    要:用滚动凝聚法制备硝苯地平缓释微丸,微丸中硝苯地平体外释药前段呈零级,后段符合Higuchi方程,持续释药时间达8h。

关 键 词:硝苯地平  缓释微丸

STUDY ON THE SUSTAINED RELEASE PELLETS OF NIFEDIPINE
He Yingju,Chen Yu,Li Liping,Sun Yiyi. STUDY ON THE SUSTAINED RELEASE PELLETS OF NIFEDIPINE[J]. West China Journal of Pharmaceutical Sciences, 1999, 14(3): 175-176
Authors:He Yingju  Chen Yu  Li Liping  Sun Yiyi
Abstract:Sustained release pellets of nifedipine have been prepared by rolling cohesion method. The drug released from pellets fitted to zeroorder process in the front part of timeconcentration curve and fitted to Higuchi's function in the later stage. They have a continuous release of 8 hours.
Keywords:NifedipineSustained release pellets
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