踝臂指数在下肢外周动脉病患者治疗中的临床应用

目的研究踝臂指数（ABI）在下肢外周动脉病患者治疗前后的变化作为评价指标的可行性．方法下肢外周动脉病患者116例，分为2组：A组（单纯药物治疗组）77例．其中男性46例，女性31例．平均年龄（67±8）岁；B组（介入治疗＋药物治疗组）39例，其中男性22例，女性17例，平均年龄（65±5）岁。详细记录每一患者的临床资料，包括年龄、性别、身高、体质量、心率、血压、空腹血糖、血脂等.并分别于治疗前、治疗后1个月、治疗后3个月检测ABI。结果①下肢外周动脉病患者治疗前ABI〈0．90：②B组治疗后1个月和治疗后3个月的ABI与治疗前相比差异均有统计学意义（P〈0．05）；③A组治疗后1个月和治疗后3个月的ABI与治疗前相比无明显变化（P〉0．05）。结论ABI在下肢外周动脉病患者的治疗中可起重要的指导作用．介入治疗能够及早改善下肢外周动脉病患者的血运．比单纯药物治疗疗效显著。

Clinical application of ankle arm index in treatment of patients with peripheral arterial disease

Objective To study feasibility of ankle arm index for treating patients with peripheral arterial disease. Methods A total of 116 patients with peripheral arterial disease were enrolled,and randomly divided into 2 groups：group A （drug treatment） ,n = 77, male 46 and female 31, mean age （67 ± 8 ） years ; group B （interventional therapy and drug treatment ）, n = 39, male 22 and female 17,mean age （65 ± 5） years. All the patients were tested for ABI by automatic analysis system of angiosclerosis before treatment,1 and 3 month after treatment. Results （1）ABI was 〈 0.90 in patients with peripheral arterial disease before treatment; （2）ABI was increased in patients with peripheral arterial disease after interventional therapy and drug treatment（P 〈 0.05 ） ;（3）ABI was non-increased in patients with peripheral arterial disease after drug treatment （P 〉 0.05）. Conclusion ABI is significant in treatment of patients with peripheral arterial disease. Interventional therapy can improve the blood circulation and the effect is better than simple drug treatment.