化疗加放疗及单用放疗治疗晚期食管癌82例疗效分析

 1990年1月至1994年10月对82例晚期食管癌随机分组研究，化疗加放疗（综合组）和单用放疗（单放组）两组进行对比研究。结果综合组与单放组1年生存率分别为68.3%和46.3%，3年生存率34.8%和8.7%，P＜0.05均有显著性差异。合并有锁骨上淋巴结转移病例中综合组与单放组1年生存率63.6%和40%，P＜0.05有显著性差异，但3年生存率28.6%和8.3%，P＞0.05无显著性差异。食管病变长度与预后在本实验中无密切关联。近期疗效综合组CR率高于单放组，吞咽症状改善情况也比单放组好。

Cure effect analysis of 82 cases of late esaphageal carcinoma is radiotherapy with chemotherapy or radiotherapy

From january in 1990 to october in 1994, we had a contrart,analysis between the test group (radiotherapy and chemotherapy) and the general (radiotherapy) on 82 cases of late esophageal carcinoma. The survival rate for one year of the test group and the general group was 68.3% and 46.3%; the survival rate for three years was 34.8% and 8.7%, It was obviously different between the two groups (P<0.05). In the cases with supraclavicular lymph nodes metastasis, the survival rate for one years of the test group and the genaral group was 63.6% and 40.0% there was obvious difference (P<0.05), but the survival rate for three years was 28.6% and 8.3%, and there was no obvious difference (P>0.05). There was no close relationship between the length of pathological Changes and the prognosis. For the recent cure result, CR rate of test group is higher than that of group is higher than that of general group. The symptom of deglutition in the test group was better.