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Vasculitis assessment and Takayasu aorto-arteritis
Authors:Paul Bacon  Rajappa Sivakumar  Debashish Danda  Ramnath Misra
Affiliation:1. Professor Emeritus, Department of Rheumatology, Medical School (East Wing), Birmingham University, Vincent Drive, Birmingham, B15 3QG, UK;2. Consultant Neurology, Chennai, India;3. Professor and Head of Rheumatology and Clinical Immunology, Christian Medical College, Vellore, India;4. Professor and Head, Department of Clinical Immunology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India;1. Max Super Specialty Hospital, Patparganj, New Delhi, India;2. Department of Rheumatology, ISIC Superspeciality Hospital, Vasant Kunj, New Delhi, India;3. A&R Clinic, Flat 2015, Sector B-2, Vasant Kunj, New Delhi 110070, India;1. Department of Rheumatology, Kalinga Institute of Medical Sciences, KIIT University, Bhubaneswar, Odisha, India;2. Department of Pulmonary Medicine, Kalinga Institute of Medical Sciences, KIIT University, Bhubaneswar, Odisha, India
Abstract:
Assessment of disease activity using clinical instruments like Birmingham Vasculitis Activity Score and Vasculitis Damage index has been extensively used both in trial and clinic setting. It has revolutionised outcome assessment for small size vasculitis as evidenced from studies carried out by the European vasculitis group. There is a need for clinical assessment tools for large vessel disease like Takayasu arteritis, which is seen more frequently in India. An attempt has been made by the Indian Rheumatology Association Vasculitis core group to validate instruments, like Disease Extent Index for Takayasu Arteritis (DEI.Tak), Indian Takayasu Activity Score (ITAS) and Takayasu Arteritis Damage Scores. Both DEI.Tak and ITAS have received interests from international investigators. Widespread usage of these instruments will pave the way to controlled clinical trials for TA.
Keywords:DEI.Tak  Indian Takayasu Activity Score  Takayasu Arteritis Damage Score
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