低强度聚焦超声与低强度脉冲超声治疗轻度创伤性膝骨关节炎:疼痛与功能的差异

背景:目前的研究显示聚焦超声与脉冲超声都能有效改善创伤性膝关节炎的病理损伤,但是2种疗法是否存在差异,尚不明确.目的:比较低强度聚焦超声与低强度脉冲超声治疗轻度创伤性膝骨关节炎的差异.方法:回顾性收集以低强度聚焦超声与低强度脉冲超声治疗轻度创伤性膝骨关节炎的患者各30例.两组患者在药物治疗的基础上,分别以低强度聚焦超声...

Low-intensity focused ultrasound and low-intensity pulsed ultrasound for mild traumatic knee osteoarthritis:differences in pain and function

BACKGROUND:Current studies have shown that both focused and pulsed ultrasound can effectively improve the pathological performance of traumatic knee osteoarthritis,but it is not clear whether there is a difference between the two therapies.OBJECTIVE:To compare low-intensity focused ultrasound and low-intensity pulsed ultrasound in the treatment of mild traumatic knee osteoarthritis.METHODS:A retrospective study was conducted in 60 mild traumatic knee osteoarthritis patients treated with low-intensity focused ultrasound(n=30)or low-intensity pulsed ultrasound(n=30).Patients in both groups received drug treatments combined with low-intensity pulsed ultrasound or low-intensity focused ultrasound for 8 weeks.Assessments and measurements were conducted before treatment,on the day after treatment,and 3 months after treatment,including Visual Analogue Scale for assessing pain,the Western Ontario and McMaster University(WOMAC)Osteoarthritis Index for assessing joint function of the affected knee,and ELISA kits for detecting serum levels of interleukin-1β,interleukin-6 and tumor necrosis factorα.RESULTS AND CONCLUSION:Compared with pre-treatment data,the Visual Analog Scale score,WOMAC score,and serum inflammatory factor levels were significantly decreased after treatment with low-intensity focused ultrasound and low-intensity pulsed ultrasound(P<0.05).This therapeutic effect lasted for at least 3 months.Low-intensity focused ultrasound induced lower Visual Analogue Scale score,WOMAC score,and serum levels of interleukin-6 and tumor necrosis factorαas compared to the low-intensity focused ultrasound.It is suggested that both low-intensity focused ultrasound and low-intensity pulsed ultrasound can effectively treat mild traumatic knee osteoarthritis,and the low-intensity focused ultrasound has a better outcome than the low-intensity pulsed ultrasound.