| 黄连素对离体灌流心脏的能量保存作用 |
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| 引用本文： | 周祖玉,孙爱民,徐建国,蓝庭剑. 黄连素对离体灌流心脏的能量保存作用[J]. 四川大学学报(医学版), 2002, 33(3): 431-433 |
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| 作者姓名： | 周祖玉 孙爱民 徐建国 蓝庭剑 |
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| 作者单位： | 四川大学基础医学与法医学院,生理教研室,成都,610041;四川大学分析测试中心 |
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| 基金项目： | 四川省科委科研基金资助 (基金编号G9710 4) |
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| 摘 要： | 目的 研究黄连素对心衰心脏的能量保存作用。方法 采用 L angendorff逆行灌流大鼠离体完整心脏的方法以维那帕米建立心衰模型 ,比较心衰和用黄连素以后再心衰心肌的高能磷酸化合物含量的变化。结果 黄连素在一定程度上能使心衰发生时心肌的高能磷酸化合物贮存量增加。结论 黄连素对心衰具有能量保存作用。
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| 关 键 词： | 黄连素 衰竭心脏 能量保存 |
| 修稿时间： | 2001-07-16 |
Effect of Energy Preservation of Berberine on Isolated Perfuse Heart |
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| Zhou Zuyu ,Sun Aimin,Xu Jianguo,Lan TingJian. Effect of Energy Preservation of Berberine on Isolated Perfuse Heart[J]. Journal of Sichuan University. Medical science edition, 2002, 33(3): 431-433 |
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| Authors: | Zhou Zuyu Sun Aimin Xu Jianguo Lan TingJian |
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| Affiliation: | Zhou Zuyu *,Sun Aimin,Xu Jianguo,Lan TingJian. *Department of Physiology,West China School of Preclinical and Forensic medicine,Sichuan University,Chengdu 610041,China |
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| Abstract: | Objective To explore the effect of energy preservation of berberine on failure heart. Methods Verapamil was used to establish the heart failure model. The concentrations of high energy phosphate in the myocardium between the failure hearts with and without pre-treatment of berberine were compared. Results Berbering increased the concentration of high energy phosphate in the failure heart. Conclusion Berberine has the effect of energy preservation on heart failure. |
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| Keywords: | Berberine Heart failure Energy preservation |
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