| 炎症性肠病患者结直肠癌化学预防研究进展 |
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| 引用本文： | 黄欢,沈骏,冉志华.炎症性肠病患者结直肠癌化学预防研究进展[J].胃肠病学,2008,13(5):312-314. |
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| 作者姓名： | 黄欢 沈骏 冉志华 |
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| 作者单位： | 上海交通大学医学院附属仁济医院消化内科,上海市消化疾病研究所,200001 |
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| 摘 要： | 炎症性肠病（IBD）主要包括溃疡性结肠炎（UC）和克罗恩病（CD）两种疾病。近年我国IBD的发病率不断上升，如未及时治疗，长期炎症将最终导致结直肠癌的发生风险增高。在各种结直肠癌预防措施中，化学预防日益受到关注。本文主要对IBD合并结直肠癌的现状和发病机制作一综述，重点介绍几种用于化学预防的药物。
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| 关 键 词： | 炎性肠疾病 结直肠肿瘤 化学预防 |
Advances in Chemoprevention of Colorectal Cancer in Patients with Inflammatory Bowel Disease |
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| HUANG Huan,SHEN Jun,RAN Zhihua.Advances in Chemoprevention of Colorectal Cancer in Patients with Inflammatory Bowel Disease[J].Chinese Journal of Gastroenterology,2008,13(5):312-314. |
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| Authors: | HUANG Huan SHEN Jun RAN Zhihua |
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| Institution: | HUANG Huan,SHEN Jun, RAN Zhihua.( Department of Gastroenterology, Renji Hospital, Shanghai Jiaotong University School of Medicine Shanghai Institute of Digestive Disease, Shanghai (200001)) |
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| Abstract: | Inflammatory bowel disease （IBD） includes ulcerative colitis （UC） and Crohn＇s disease （CD）. The incidence of IBD has increased in China in recent years, and patients with IBD will have high risk for colorectal cancer （CRC） if not treated in time. More attention has been paid to chemoprevention of CRC. This review article introduced the present status and pathogenesis of IBD patients complicated with CRC, with focus on several agents used for chemoprevention. |
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| Keywords: | Inflammatory Bowel Diseases Colorectal Neoplasms Chemoprevention |
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