Akuter thrombembolischer ST-Hebungs-Infarkt bei einem Patienten mit essenzieller Thrombozytose |
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Authors: | Dr C Doesch AE May G Toncar-Pflumm N Anders T Geisler S Kröber R Kandolf M Gawaz |
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Institution: | 1. Medizinische Klinik III, Universit?tsklinikum Tübingen, Otfried-Müller-Str. 10, 72076, Tübingen, Deutschland 2. Institut für Pathologie, Universit?tsklinikum Tübingen, Tübingen, Deutschland
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Abstract: | A 48-year-old man presented with acute chest pain and a greatly increased platelet count. Emergency coronary angiographc revealed thrombotic occlusion of the right coronary artery. Coronary angioplasty and stenting were successfully combined with intracoronary abciximab administration. Due to inadequate postinterventional platelet inhibition an intensified dual antiplatelet therapy with acetylsalicylic acid (ASS) and clopidogrel was applied to prevent stent thrombosis. Due to the thrombo-embolic complication and a platelet count over 1 million/µl a cytoreductive treatment with hydroxyurea was initiated. |
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