基于自主神经功能的不同选穴原则对无先兆性偏头痛患者针刺干预的随机对照研究

目的:基于自主神经功能探讨不同选穴原则干预无先兆性偏头痛患者的治疗效果.方法:2016年11月至2018年6月收集浙江中医药大学附属第三医院针灸科符合纳入标准的偏头痛患者84例,随机分为自主神经组41例(脱失1例)和常规治疗组40例(脱失2例),治疗频率为3次/周,均治疗2周,8周后回访.缓解期检测心率变异性特征,包括...

Randomized controlled study of different acupoints selection principles based on autonomic nerve function in patients with migraine without aura

Objective:To explore the therapeutic effects of different acupoints selection principles in patients with migraine without aura and to elucidate the role of autonomic dysfunction in migraine.Methods:Patients with migraine without aura who met the inclusion criteria from Acupuncture and Moxibustion Department,The Third Affiliated Hospital of Zhejiang Chinese Medical University in November 2016 to June 2018 were randomly assigned to the autonomic(40 cases with 2 cases dropout)and conventional acupoint groups(41 cases with 1 case dropout)after informed consent.The frequency of treatment was 3 times/week,both were treated for 2 weeks,and follow-up at 8 weeks after treatment.The heart rate variability characteristics were detected during the remission period,including the frequency domain index and the time domain index.The heart rate variability characteristic test and the simple McGill pain score were simultaneously performed at the three points of the attack period,the first treatment,and the end of the treatment period.The simplified McGill pain score was performed again in the follow-up visit and the safety indicators were tested throughout.Results:There was no significant difference in heart rate variability between the two groups during remission.And there was also no significant difference in frequency domain indicators after treatment.While in the domain index time,compared with the onset,the normal N-N interval standard deviation(SDNN)of the two groups was statistically different at 24 h(P<0.05).After the first treatment in the autonomic nerve group,compared with the onset,there was also a statistical difference in the standard deviation(SDANN)of the mean value per 5 min of the N-phase(P<0.05).In the McGill scale scores of the two groups,the autonomic nerve group had multiple scores significantly lower than the conventional acupoint group(P<0.01,P<0.05).In addition,the total effective rate at 8 weeks was 85.4%and 80.0%,respectively,and no serious adverse events occurred.Conclusion:Acupuncture has immediate and long-term effects on migraine patients.Both conventional acupoints and autonomic acupoints enhance sympathetic activity.Acupoints for autonomic nerve function have certain advantages,and it has certain reference value how to choose the acupoints between the clinical treatment of migraine.