中药寒热药性研究方法综述

以现代科技方法对中医药理论进行科学诠释,是中医药发展、发扬和标准化所亟需的重要一步,对药性的研究是其中的重要一环。中药四性理论是中药药性理论体系的核心,现代科技的不断发展为中药寒热药性研究提供了新的手段与途径,推动其进入分子水平,除对其属性表征与物质基础的研究外,还开始探寻其内在机制。文章着重从中药物象、基因组学、蛋白组学和代谢组学等角度对中药寒热药性研究进展进行综述,以展示近年来中药寒热药性研究的不同思路与方法。

Review on research methods of cold and heat property of Chinese materia medica

It is an urgent step for the development and standardization of traditional Chinese medicine to interpret its theory with modern scientific and technological methods,of which the research on the properties Chinese materia medica is the key.The theory of four properties of Chinese materia medica is the core of the Chinese materia medica property theory.With the continuous development of modern science and technology,new means and approaches are provided for the study of the cold and heat of Chinese materia medica,which makes the research into the molecular level.In addition to the study of its attribute representation and material basis,it also begins to explore its internal mechanism.In this paper,the study of the cold and heat of Chinese materia medica is reviewed from the perspectives of the image of Chinese materia medica,genomics,proteomics and metabonomics,trying to show different research ideas and methods in recent years.