| 急性髓系细胞白血病bcl—2表达水平与预后的关系 |
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| 引用本文： | 柳金 曹萍. 急性髓系细胞白血病bcl—2表达水平与预后的关系[J]. 湖南医科大学学报, 2000, 25(3): 265-266 |
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| 作者姓名： | 柳金 曹萍 |
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| 摘 要： | 采用免疫组化方法测定５８例急性髓系细胞白血病患者抗凋亡基因ｂｃｌ－２蛋白表达水平，分析ｂｃｌ－２基因与临床预后关系。结果表明，高表达ｂｃｌ－２患者，化疗反应差，预后不良，提示ｂｃｌ－２表达水平可作为判断急性髓系细胞白血病预后的重要指标之一。
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| 关 键 词： | 急性髓细胞性白血病 细胞凋亡 bcl－2蛋白 |
Relationship between the expression of bcl-2 apoptosis and acute myelogenous leukemia prognosis] |
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| J Liu,P Cao,Z H Qi. Relationship between the expression of bcl-2 apoptosis and acute myelogenous leukemia prognosis][J]. Bulletin of Hunan Medical University, 2000, 25(3): 265-266 |
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| Authors: | J Liu P Cao Z H Qi |
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| Affiliation: | Department of Hematology, Xiangya Hospital, Hunan Medical University, Changsha 410008. |
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| Abstract: | In order to check the anti-apoptosis gene bcl-2 protein expression in 58 AML patients we used the immunohistochemical method, and analyse the relationship between bcl-2 protein and prognosis of AML. The result showed that the high expression of bcl-2 protein was related to poor clinical prognosis of AML. This shows that the expression of bcl-2 gene can serve as an index for the prognosis of AML. |
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