无环鸟苷治疗小儿疱疹性口腔炎疗效观察

目的：探讨无环鸟苷用于小儿疱疹性口腔炎的治疗效果及临床价值。方法：对2009年1月--2010年1月期间收治的40例小儿疱疹性口炎患者治疗方法进行回顾性分析，全部惠儿在入院后进行一般对症治疗和抗感染治疗后，随机分为两组：治疗组20例，采用无环鸟苷静滴治疗，对照组20例，采用病毒唑静滴治疗。在治疗5天后观察两组疗效。结果：治疗组20例：显效17例，有效3例，无效1例，显效率85．0％，总有效率95．0％。对照组20例：显效8例，有效7例，无效5例，显效率40．0％，总有效率75．0％。两组显效率比较（P〈0．05）有显著差异。结论：无环鸟苷治疗小儿疱疹性口腔炎疗效较好，且使用安全、无明显、毒副作用，值得临床推广应用。

The observation of Acyclovir treatment efficacy to children with herpes simplex

Objective：To investigate the effects and clinical value of acyclovir to children with herpes simplex. Methods：40 patients with herpes stomatitis treated in our hospital from January 2009 -- 2010 were retrospectively analyzed. After the general symptomatic treatment and anti--infection therapy, all childrenwere randomly divided into two groups： treatment group 20 eases, with intravenous acyelovir treatment, control group of 20 patients treated with intravenous ribavirin. The treatment effects were observed after 5 days. Results：20 patients in treatment group： 17 eases were markedly 3 cases were effective, 1 patient was in effective, the excellence rate was 85.0% and the total efficiency was 95.0%. 20 patients in control group： 8 eases were markedly effective, 7 eases were effective, 5 eases were ineffective, the excellence rate was 40.0% and the total efficiency was 75.0%. The efficiency of the two groups was significantly different （P〈0.05） . Conclusion：Acyelovir treatment to children with herpetic stomatitis has better effect, and it is safe, has no obvious side effect, which is worthy to get clinical application.