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2011年蚌埠中药注射剂不良反应报告分析
引用本文:丁明聪,叶根深,卢家梅,张树强. 2011年蚌埠中药注射剂不良反应报告分析[J]. 安徽医药, 2013, 17(3): 510-513
作者姓名:丁明聪  叶根深  卢家梅  张树强
作者单位:安徽省蚌埠市中医院;安徽省蚌埠市第一人民医院;安徽省蚌埠市药品不良反应监测中心,安徽,蚌埠,233000
摘    要:目的了解蚌埠地区中药致药品不良反应(ADR)的发生情况。方法对2011年度蚌埠地区上报的385例中药致ADR报告,按性别、年龄、药品类别、制剂、ADR临床表现等进行统计、分析。结果 385例ADR中,40岁以上患者ADR发生率较高(82.3%),ADR发生率以补益类、活血类、中药来源的化学药品注射剂较高,发生不良反应较多的制剂品种有:痰热清、双黄连等;主要的ADR类型为皮肤及其附件损害,占22.2%。结论 40岁以上患者要慎用中药注射剂,以减少ADR的发生率。

关 键 词:中药  药品不良反应

Traditional Chinese drug adverse reactions in Bengbu city during 2011
Affiliation:DING Ming-cong,YE Gen-shen,LU Jia-mei,et al(1.Traditional Chinese Medical Hospital;2.The 1st People's Hospital of Bengbu;3.Adverse Drug Reactions Monitoring Center,Bengbu,Anhui 233000,China)
Abstract:Objective To investigate the situation of traditional Chinese drug(TCD)adverse reactions in Bengbu city.Methods In respect of gender,age,drug category,preparation,clinical manifestations of ADR,and so on,385 reports of TCD adverse reactions in Bengbu city reported in 2011 were statistically analyzed.Results In 385 reports of TCD adverse reactions,ADR most occurred in patients over the age fo 40(82.3%),and most occurred in categories of Beneficial TCD,promoting circulation TCD and chemical injection from TCD,and preparations such as Tanreqing,Shuanghuanglian,etc.Primary ADR is harm to and its accessory structures,which accounted for 22.2% of the total.Conclusion To reduce incidence rate of ADR,we should be more careful of TCD clinical application in patients over the age of 40.
Keywords:traditional Chinese drug(TCD)  ADR
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