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| 丹皮酚的抗炎作用研究 | |
| 引用本文： | 武海军,徐继辉,李月玲,刘和莉,杨玉梅. 丹皮酚的抗炎作用研究[J]. 包头医学院学报, 2008, 24(3): 238-239 |
| 作者姓名： | 武海军 徐继辉 李月玲 刘和莉 杨玉梅 |
| 作者单位： | 包头医学院药理学教研室,内蒙古包头,014010;包头医学院药理学教研室,内蒙古包头,014010;包头医学院药理学教研室,内蒙古包头,014010;包头医学院药理学教研室,内蒙古包头,014010;包头医学院药理学教研室,内蒙古包头,014010 |
| 摘 要： | 目的：观察二氧化碳（CO2）超临界提取的丹皮酚的抗炎作用。方法：用醋酸导致小鼠腹腔毛细血管通透性增加；用角叉菜胶导致大鼠足跖肿胀。结果：丹皮酚50．0、25．0、12．5mg,／kg灌胃给药，可明显降低小鼠腹腔毛细血管通透性；丹皮酚32.0、16．0、8．0mg,／kg灌胃给药，能显著抑制角叉菜胶所引起的大鼠足肿胀。结论：经CO2超临界提取的丹皮酚具有明显的抗炎作用。 |
| 关 键 词： | 丹皮酚 二氧化碳 超临界提取 抗炎 |
| 修稿时间： | 2007-07-28 |
Study of Anti-inflammatory Effects of Paeonol |
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| WU Haijun,XU Jihui,LI Yueling,LIU Heli,YANG Yumei. Study of Anti-inflammatory Effects of Paeonol[J]. Journal of Baotou Medical College, 2008, 24(3): 238-239 | |
| Authors: | WU Haijun XU Jihui LI Yueling LIU Heli YANG Yumei |
| Affiliation: | WU Haijun,XU Jihui,LI Yueling,LIU Heli,YANG Yumei(Department of Pharmacology,Baotou Medical College,Baotou 014010,China) |
| Abstract: | Objective:To observe the anti-inflammatory effects of paeonol obtained through supercritical CO2 fluid extraction.Methods: Anti-inflammatory effect of paeonol was observed by examining the permeability increase of mouse abdominal capillary induced by acetic acid and carrageenin-induced paw edema.Results: Gastric perfusion of paeonol at the dose of 50.0mg/kg,25.0mg/kg and 12.5mg/kg could markedly inhibit acetic acid-triggered increase of abdominal capillary permeability;Gastric perfusion of paeonol at the do... |
| Keywords: | Paeonol Supercritical CO2 Fluid extraction Anti-inflammatory |
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