| CD133在胰腺癌中的表达及其意义 |
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| 引用本文： | 王烜,邓明明,杜光红,贺凯. CD133在胰腺癌中的表达及其意义[J]. 中国临床医学, 2009, 16(4): 556-557 |
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| 作者姓名： | 王烜 邓明明 杜光红 贺凯 |
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| 作者单位： | 1. 四川省泸州医学院附属医院消化内科,四川泸州,646000
2. 四川省泸州医学院附属医院肝胆外科,四川泸州,646000 |
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| 摘 要： | 目的：探讨CD133在胰腺癌中的表达及其与胰腺癌临床病理学特征之间的关系。方法：用免疫组织化学法检测58例胰腺癌、癌旁组织、正常胰腺组织中CD133的表达，比较CD133表达与临床病理等因素之间的相关性。结果：CD133在胰腺癌中表达为63．8％（37／58），在胰腺癌、癌旁组织、正常组织CD133表达呈下降趋势。CD133表达与淋巴转移、临床病理分期呈正相关性（P〈0．05），与胰腺癌组织学分化呈负相关（P〈0．01）。结论：CD133作为胰腺癌肿瘤干细胞的表面标记物，与胰腺癌发生、发展密切相关，与胰腺癌的临床分期、组织分化以及淋巴转移密切相关。
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| 关 键 词： | 胰腺癌 CD133 淋巴转移 |
Expression of CD133 in Pancreatic Cancer and Its Significance |
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| WANG Xuan,DENG Mingming,DU Guanghong,HE Kai. Expression of CD133 in Pancreatic Cancer and Its Significance[J]. Chinese Journal Of Clinical Medicine, 2009, 16(4): 556-557 |
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| Authors: | WANG Xuan DENG Mingming DU Guanghong HE Kai |
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| Affiliation: | WANG Xuan DENG Mingming DU Guanghong HE Kai Department of Gastroenterology,Department of Hepatobiliary Surgery,Affiliated Hospital of Luzhou Medical College,Luzhou 646000,China |
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| Abstract: | Objective:To investigation the expression and significance of CD133 in pancreatic cancer and their association with the clinical pathologic characters. Methods:Immunohisto-chemistry staining was used to detect the expression of CD133 in 58 pancreatic cancer tissues,pericarcinomatous tissues and nontumorous tissues. The correlations among the variety of expression of CD133 and pancreatic clinical pathologic characters were statistically analyze. Results:The expression rate of CD133 was 63.8%(37/58)and it was... |
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| Keywords: | Pancreatic cancer CD133 Lymphatic metastasis |
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