四种溶脲脲原体对精子穿卵试验的作用比较

分别用血清型４、９、１０、１２四种溶脲脲原体按２０￣４０颜色变化单位（ＣＣＵ）／精子的浓度与正常生育男性精子一同孵育。结果发现，部分感染的精子尾部有绒毛状附着物；血清型４、１２溶脲脲原体与精子共同孵育后，精子活率及活力明显下降，血清型９、１０溶脲脲原体对精子活率及活力无明显影响。血清型４、９、１０、１２溶脲脲原体均使精子穿卵值（ＳＰＡ）明显降低（分别为６．５０％、１０．４５％、９．６０％和６．４０％），对照组为４９．３３％。提示溶脲脲原体不仅可能影响精子的活率与活力，而且可影响精卵相互作用乃至融合过程，溶脲脲原体的致病作用与其血清型有关。

Comparing of Effects of Four Strains of Ureaplasma Urealyticum on Hamster Egg Penetration Assay by Human Spermatozoa

Four strains of U. urealyticum, serotype 4, 9, 10, and 12, were incubated overnight withthe spermatozoa from normal fertile men respectively at the concentration of 20-40 CCU/spermatozoon. It was shown that fuzzy appearance was noticed at the tails of infected spermatozoa.Sperm viability and motility were declined dramatically after incubated with serovar 4 and 12,while serovar 9 and 10 being no significant effect on sperm viability and motility; significant decline of SPA was found after treated by U. urealyticum 4, 9, 10 and 12, the penetration rates being 6. 50%, 10. 45%, 9. 60% and 6. 45% respectively as compared with the normal value of 49.33%.The results inplied that U. urealyticum not only has deteriorating effect on sperm viability and motility, but also interfere with sperm-ovum interaction and/or fusion. A close relationship between U. urealyticum serovar and its pathogenicity was claimed in this study.