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Pneumocystis carinii f. sp. hominis is not infectious for SCID mice
Authors:Durand-Joly Isabelle  Aliouat El Moukhtar  Recourt Céline  Guyot Karine  François Nadine  Wauquier Michèle  Camus Daniel  Dei-Cas Eduardo
Affiliation:Ecologie du Parasitisme, Institut Pasteur de Lille, 1 rue du Prof-Calmette-BP 245, 59019 Lille, France. isabelle.joly@pasteur-lille.fr
Abstract:The infectious power of Pneumocystis carinii f. sp. hominis was explored by inoculating SCID mice intranasally with either P. carinii f. sp. hominis or P. carinii f. sp. muris isolates. Only mice inoculated with mouse parasites developed Pneumocystis pneumonia, as assessed by microscopy and PCR. These results suggest that humans do not contract pneumocystosis from animals.
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