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丹芷胶囊抗炎镇痛作用的实验研究
引用本文:黄山,卞慧敏,郭立玮,姜淼,陆凯磊. 丹芷胶囊抗炎镇痛作用的实验研究[J]. 中华中医药学刊, 2006, 24(2): 288-289
作者姓名:黄山  卞慧敏  郭立玮  姜淼  陆凯磊
作者单位:南京中医药大学植物药研究与新药开发中心,江苏,南京,210029
摘    要:目的:评价丹芷胶囊的抗炎、镇痛作用。方法:用二甲苯致小鼠耳廓肿胀试验、角叉菜胶致大鼠足跖肿胀试验,考察丹芷胶囊的抗炎作用;用小鼠醋酸扭体法和热板法,考察丹芷胶囊的镇痛作用。结果:丹芷胶囊能明显抑制二甲苯致小鼠耳廓肿胀和角叉菜胶致大鼠足跖肿胀;对醋酸致小鼠扭体反应有明显的抑制作用,提高小鼠热痛阈值。结论:丹芷胶囊有明显的抗炎、镇痛作用。

关 键 词:丹芷胶囊  抗炎作用  镇痛作用
文章编号:1009-5276(2006)02-0288-02
修稿时间:2005-08-27

Experimental Study on Anti- Inflammatory Effect and Analgesic Effect of DanZhi Capsules
HUANG Shan,BIAN Hui-min,GUO Li-wei,JIANG Miao,LU Kai-lei. Experimental Study on Anti- Inflammatory Effect and Analgesic Effect of DanZhi Capsules[J]. Chinese Archives of Traditional Chinese Medicine, 2006, 24(2): 288-289
Authors:HUANG Shan  BIAN Hui-min  GUO Li-wei  JIANG Miao  LU Kai-lei
Abstract:Objective:To study the anti-inflammatory effect and analgesic effect of DanZhi capsules.Methods: Models of acute inflammatory reactions of xylene-induced mouse ear edema,carrageena-induced rat paw edema were performed to study the anti-inflammatory effects.Methods of acetic acid induced writhing and hot-plate test in mice were used to study the analgesic effect.Results:DanZhi capsules significantly suppressed xylene-induced mouse ear edema and carrageena-induced rat paw edema.The writhing times of mice induced by acetic acid were decreased and pain threshold was remarkably improved by DanZhi capsules.Conlusion: DanZhi capsules have significantly effects of antiinflammatory and analgesic effects.
Keywords:DanZhi capsules  anti-inflammatory effect  analgesiceffect
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