血浆置换术救治中重度毒鼠药中毒的效果观察

目的 探讨血浆置换术在抢救严重毒鼠药中毒患者中的应用效果。方法 71例中重度的毒鼠药中毒患者按年龄、性别、服毒剂量分成PE组和常规一般疗法对照组。对照组患者采用催吐、洗胃、导泻、对症支持治疗的传统方法，PE组在应用一般疗法的基础上进行血浆置换术。结果 PE组中度中毒患者全部抢救成功，重度患者抢救成功率达87．5％；而对照组中度中毒患者抢救成功率86．36％，重度患者抢救成功率65％；两组的结果差异有显著性意义。结论 应用血浆置换术抢救严重的毒鼠药中毒患者临床疗效显著，在一般疗法的基础上，进行PE治疗，能更有效地救治病人，提高抢救成功率。

Effect of Plasma Exchange for Serious Intoxication Patients with Mice Toxicant

Objective To investigate the effect of plasma exchange for the serious intoxication patients with mice toxicant. Methods 71 patients were divided into two groups as follow: PE group and control group. The patients of control group were gave emetic, gastric lavage, catharsis and symptomatic treatment;The patients of PE group applied plasma exchange therapy base on the general treatment. Results In PE group, all secondary patients and 87.5% of the serious patients were cured. In control group, only 86.36% of secondary patients and 65% of the serious patients were cured. Conclusions Plasma exchange were effect for the serious intoxication patients with mice toxicant.