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ERK信号通路与肝纤维化
引用本文:陈达凡,李建英,郑伟达,王小众. ERK信号通路与肝纤维化[J]. 国际消化病杂志, 2007, 27(5): 370-372,391
作者姓名:陈达凡  李建英  郑伟达  王小众
作者单位:福建医科大学附属协和医院消化研究所,350001
摘    要:
细胞外信号调节激酶是丝裂原激活蛋白激酶家族的重要成员。近年来发现其与肝纤维化的关系密切,可从多方面影响肝纤维化的形成。通过干预细胞外信号调节激酶通路,研究肝纤维化的发病机制和药物治疗是有希望的途径。

关 键 词:细胞外信号调节激酶  肝纤维化  肝星状细胞
修稿时间:2007-01-15

ERK signaling pathway and liver fibrosis
CHEN Da-fan, LI Jian-ying , ZHENG Wei-da,et al.. ERK signaling pathway and liver fibrosis[J]. International Journal of Digestive Disease, 2007, 27(5): 370-372,391
Authors:CHEN Da-fan   LI Jian-ying    ZHENG Wei-da  et al.
Abstract:
The extracellular signal-regulated kinase(ERK) is an important member of mitogen-activated protein kinase(MAPK) family.The ERK signaling pathway is involved in liver fibrosis in many ways.It is a promising way to study the pathogenesis and therapy of liver fibrosis through intervention of ERK signaling pathway.
Keywords:Extracellular signal-regulated kinase  Liver fibrosis  Hepatic stellate cell
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