羊水粪染与羊膜腔感染的关系

【摘要】 目的 :探讨羊水粪染与羊膜腔感染的关系。方法 :选择未临产且胎膜完整的剖宫产产妇 5 6例 ,根据术中所见羊水性状分为羊水清亮组、羊水Ⅰ～II度粪染组和羊水III度粪染组。于剖宫产术中取羊水用双抗体夹心ELISA法测IL 6含量 ,取胎盘胎膜做病理检查以了解有无炎性细胞浸润 ,并记录新生儿Apgar评分 ,观察产妇术后有无产褥感染。结果 :3组羊水中IL 6含量差异无显著性 ,3组胎盘标本病理检查示炎性细胞浸润之差异亦无显著性 ,而羊水粪染组新生儿窒息发生率较清亮组明显增加 (P <0 .0 5 )。结论 :羊水粪染尤其是III度粪染是胎儿窘迫的标志 ,而与羊膜腔感染无明显相关性。

Meconium-stained amniotic fluid and intra-amniotic infection

Objective To explore the relationship between meconium-stained amniotic fluid and intra-amniotic infection. Methods Fifty-six women of cesarean section with intact membrane and without parturient were divided into 3 groups according to the property of amniotic fluid (no meconium, Ⅰ～Ⅱdegree meconium stainedness, and Ⅲ degree mecomium stainedness). The content of interleukin-6 in amniotic fluid was measured with ELISA . The infiltration of inflammatory cells in the placenta and its membrane was determined by the pathological diagnosis. The neonatal Apgar score and puerperial infection after the surgery were analyzed. Results There were no significant differences in the content of IL-6 in amniotic fluid and in the infiltration of inflammatory cells among the 3 groups. But the rate of neonatal asphyxia in the meconium-stained cases was significantly higher than that without meconium. Conclusion Meconium-stained amniotic fluid is a marker of fetal distress, but it is not related to intra-amniotic infection.