磁共振PWI联合DWI在老年急性期脑梗死中的应用价值

目的 探讨灌注加权成像(PWI)联合弥散加权成像(DWI)对急性期脑梗死的诊断价值.方法 采用回顾性研究方法,收集56例发病时间1～72 h(其中20例为超急性期脑梗死,发病时间＜6 h;36例为急性期脑梗死,发病时间7～72 h)的老年脑梗死病人的临床及影像资料.所有病人均进行PWI和DWI检查,主要观察指标:患侧脑...

Application value of combined magnetic resonance PWI and DWI in diagnosis of acute cerebral infarction

Objective To investigate the application value of perfusion weighted imaging(PWI)combined with diffusion weighted imaging(DWI)in the diagnosis of acute cerebral infarction.Methods The clinical and imaging data of 56 elderly patients with cerebral infarction within 1 h to 72 h after the onset of symptoms were collected by the retrospective study.Twenty patients were in hyperacute phase with time since stroke onset<6 h,and 36 patients were in acute phase with time since stroke onset 7-72 h.All the patients were examined by PWI and DWI.The main items for observation included abnormal regions and parameters of DWI and PWI,such as cerebral blood flow(CBF),cerebral blood volume(CBV),mean transient time(MTT)and time to peak(TTP)in affected brain tissue of cerebral infarction.Results PWI showed that MTT and TTP were prolongated.In hyperacute phase,the level of CBF decreased in 18 cases(90.00%)and remained normal in 2 cases(10.00%);the level of CBV decreased in 10 cases(50.00%),remained normal in 5 cases(25.00%),and increased in 5 cases(25.00%).In acute phase,the level of CBF decreased in 36 cases(100.00%);the level of CBV decreased in 26 cases(72.22%),remained normal in 5 cases(13.89%),and increased in 5 cases(13.89%).DWI in hyperacute phase showed less abnormal signal region than PWI in all cases.In acute phase,there were 21 cases with DWIPWI.Conclusions DWI can show the necrotic area of cerebral infarction,while PWI can show both the necrotic area of cerebral infarction and its surrounding ischemic penumbra.Combined use of DWI and PWI can define the range of cerebral infarction and ischemic penumbra.